During the study, 63% of elective colorectal surgery patients received 3 g cefazolin instead of a 2 g dose. The increased dose was not associated with decreased SSIs in the study population.

[2,3] Cefazolin is one of the most commonly used antimicrobials in these patients because of its broad antimicrobial spectrum, favorable pharmacokinetics, and safety. [4,5,6] Heparin is frequently ...