and inactive (guanosine diphosphate [GDP]–bound) states, offering a window during which “off-state” inhibitors might engage with KRAS. Studies by Jeffrey Klomp et al. 6 and Jennifer Klomp et al.

Yulan Xiong, associate professor of neuroscience at UConn Health, and her team have discovered one more piece of the puzzle ...

The regeneration of the hairpin would be powered by consumption of external fuel hairpin motifs, analogous to the exchange of guanosine diphosphate (GDP) for GTP by microtubular subunits.

Yulan Xiong and her team have discovered a much-searched-for regulator that plays a key role in genetic causes of Parkinson's ...

Upon binding of the tRNA-amino acid complex in the A site, GTP is cleaved to form guanosine diphosphate (GDP), then released along with EF-Tu to be recycled by EF-Ts for the next round.

and `off' when guanosine diphosphate (GDP) is bound. Ras protein is one of the simplest G proteins, and our studies revealed the structural basis for understanding how this molecular switch works. We ...