Abstract & Introduction Activated Hepatic Stellate Cells as a Target ... expression in damaged livers in activated HSCs rather than in parenchymal cells. [8] A controversial issue is whether ...

In normal liver, hepatic stellate cells (HSCs) are nonparenchymal, quiescent cells whose main functions is to store vitamin A and probably to maintain the normal basement membrane-type matrix.

with hepatic stellate cells (HSCs) playing a crucial role in this process. New insights on regulation of HSCs appear in a ...

Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-healing ...

When TGF-β is converted from its biologically inactive form (LTGF-β) to its active form (TGF-β), it promotes fibrosis by activating hepatic stellate cells (HSCs). These cells transform into ...