Mesenchymal stem cells (MSCs) once looked likely to avoid such attacks. However, recent studies have shown that some MSCs are more immunogenic than others. Liver-derived MSCs, such as Promethera ...
Therefore, there is no direct proof that these cells remain in the developing liver. It is likely that the number of actual stem cells declines during development and only quiescent potential stem ...
Liver epithelial cell lines are considered the cell culture counterpart of liver stem/progenitor cells (for a detailed review, see Grisham and Thorgeirsson [10]). Several laboratories, including ...
HHMI researchers solve a longstanding mystery about the origin of new cells in the liver. Howard Hughes Medical Institute (HHMI) scientists have identified stem cells in the liver that give rise to ...
The results were published in Cell Stem Cell in 2017. The cells, known as chemically-induced liver progenitors (CLiPs), can be transplanted back into the rodent’s liver via the portal vein or ...
In healthy liver, quiescent hepatic stellate cells (HSCs ... We have developed a protocol to direct the differentiation of human induced pluripotent stem cells (iPSC) to HSCs. The final HSC–like ...
They can also test how drugs might affect different organs such as the heart or the liver by programming stem cells to acquire properties of the organ the drugs are targeting. They can also be ...