Selecting an appropriate mouse model is one of the most important decisions a pre-clinical researcher can make. Which is best suited for immuno-oncology? Cancer research and drug discovery has ...

Our laboratory is interested in the use of mouse models of prostate cancer to explore the pathogenesis of prostate cancer and its response to treatment. We have used the SV-40 based TRAMP model of ...

The laboratory mouse is widely considered the model organism of choice for studying the diseases of humans, with whom they share 99% of their genes. A distinguished history of mouse genetic ...

The understanding of the molecular mechanisms of DM1 pathogenesis has led to development of several therapeutic approaches some of which are being testing using mouse models established in the lab.

The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory mice are usually of the species Mus ...

Establishing a breath analysis approach employing mice in a controlled lab setting as a surrogate ... has established the feasibility of mouse models for breath VOC study, however the number ...

In a mind-blowing breakthrough, scientists have managed to create a mouse using genetic tools older than life on earth itself. This was by using a gene from single-celled forms of life ...

The goal of our laboratory is to understand when, why, and how immune cells become unresponsive to tumors or self-destructive in autoimmune diseases. We develop genetic cancer mouse models that mimic ...

Nano-sized, tumor-targeting particles induced self-destruction of cancer cells in preclinical studies. A new twist on a ...

Laboratory research led by MSK and Cold Spring Harbor Laboratory demonstrates the ... New Research in Mice Finds New MSK research combined sophisticated genetically engineered mouse models and ...

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends ...

Researchers say study represents a resource that could also help to dissect Y-gene functions in other tissues.