How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

In the new study, researchers homed in on a part of the viral machinery called the viral polymerase complex, a group of ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

RNA polymerase is an enzyme that is responsible for copying a DNA sequence into an RNA sequence, duyring the process of transcription. As complex molecule composed of protein subunits, RNA ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure of the Nipah virus polymerase complex (the ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional ...

Gene expression is linked to RNA transcription, which cannot happen without RNA polymerase. However, this is where the similarities between prokaryote and eukaryote expression end. Central to the ...

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this ...

Antimicrobial resistance (AMR) in waterways presents a critical threat. If commonly used antibiotics are deemed useless, decades of progress in human medicine and agriculture could be undermined.

Newer treatments target pathways like Delta-like ligand 3, poly-ADP-ribose polymerase, and histone deacetylase to address ...

There are a variety of different types of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is responsible for creating messenger RNA (mRNA), which is the main ...