Tatsuya Yoshida, Mikito Takefuji, and Toyoaki Murohara in the Department of Cardiology, Nagoya University Graduate School of Medicine, identified an enzyme, alpha-kinase 2 (ALPK2) that is specifically ...

Researchers have discovered how a particular protein affects the growth and spread of colon cancer in humans. The study not ...

NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...

A thorough examination of modern drugs that target particular receptors and metabolic pathways for glucose and fat metabolism is presented. Recent research has revealed innovative targets and ...

A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...

A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct ...

Xi’an Xintong Medicine Research Co. Ltd. has synthesized tyrosine-protein kinase JAK3 inhibitors reported to be useful for the treatment of rheumatoid arthritis, alopecia areata, vitiligo, asthma, ...

Windtree Therapeutics (WINT) announced the issuance of a patent in Japan for “Inhibitors of atypical protein kinase C and their use in treating ...