Three different hTERT-immortalized human primary renal proximal tubule epithelial cells (RPTEC) were modified and tested for functionality and stable expression of the OAT1, OCT2, and OAT3 proteins.

It appears that because of the extremely acute nature of the experiment these animals were able to flush their kidneys free of crystals before toxic damage to the renal epithelium produced ...

Previous work by our group definitively established that HIV can cause kidney disease through direct infection of the renal epithelium. We found that the kidney is a reservoir for replicating virus ...

RCCs derived from the renal epithelium compose 85% of all renal cancers (conventional or papillary) and present as advanced disease in a quarter of patients, with a median time of survival for ...

Kidney stones are largely composed of calcium oxalate (CaOx), which can cause serious renal inflammation and damage to renal tubular epithelial cells, with the CaOx crystals gradually accumulating and ...