Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...
and hepatic stellate cells (which activate during liver injury to produce scar tissue). “Given the complexity of the cells' shapes, even modern cell-segmentation technology can struggle to catch ...
The HepaStem cells have immunomodulatory properties, similar to other MSCs, and act on the hepatic stellate cells that ... they retain some of the features shaped by their original niche, enabling ...
As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...