often resulting in a frameshift Cystic fibrosis Chromosomal mutation Inversion One region of a chromosome is flipped and reinserted Opitz-Kaveggia syndrome Deletion A region of a chromosome is ...

Because gene-level mutations are more common than chromosomal mutations ... be inserted in place of a guanine nucleotide. With base substitution mutations, only a single nucleotide within a ...

Although the genetic interactions among mutations ... to an amino acid substitution which disrupts the enzyme activity, while ...