This study presents fundamental insights into overcoming resistance in hormone receptor-positive breast cancer by demonstrating that sustained CDK4/6 inhibitor treatment, either alone or in ...

Drugs are metabolised differently by people of different age groups, ethnicities among other factors. There is a need for therapeutic drug monitoring (testing that measures the amount of a ...

In drug discovery, very little of what’s learned ... Targeting RNA rather than proteins is at the heart of RNAi-based medicines’ therapeutic effect, as well as the advantages of their ...

Here at The Institute of Cancer Research, we are a powerhouse of drug discovery. Since 2005, 13 of our drugs have entered clinical trials, and many more current cancer medicines are rooted in ...

Multi-Modal Models: A multi-modal discovery approach was implemented that engineered-in potency against the novel target and engineered-out a specific off-target interaction. The NCE library displayed ...

Insilico Medicine (“Insilico”), a clinical stage generative artificial intelligence (AI)-driven biotechnology company has recently announced the breakthrough study achieved in collaboration with a ...

In this study, pharmacogenomics and therapeutic drug monitoring were used to evaluate the clinical effectiveness of genotyping chronic pain patients on analgesic therapy. It was hypothesized that ...

Shares of Tectonic Therapeutic (NASDAQ:TECX) plunged on Tuesday after a federal website on clinical trials indicated that Eli Lilly (NYSE:LLY) has terminated a mid-stage trial for its experimental ...

Scientists develop DNA nanorobots capable of modifying artificial cells. Scientists at the University of Stuttgart have ...

Medicare spending on cancer drugs may not be associated with the drugs’ clinical benefits, such as overall survival or progression-free survival.