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生物通
1 年
《研究思路解析》全新发布!
最后,总结了circRNA-miRNA、circRNA-蛋白互作研究的技术方法。 lncRNA m6A:(1)“m6A转换器”的功能(2)影响lncRNA与蛋白互作或者与miRNA的结合;(3)m6A作为lncRNA降解的标志。 circRNA m6A:调控circRNA稳定性、促进非帽依赖的翻译、影响circRNA与蛋白互作、控制“自身的 ...
生物通
1 年
LncRNA:从“转录噪声”到科研高地的逆袭
系统地整合了lncRNA的转录因子结合位点和m6A修饰位点,并提供了SNP对lncRNA转录和修饰的综合作用。他们收集了lncRNA中推定的开放阅读框架,并在ORF中确定了同义和非同义SNP。研究人员还从文献中收集了lncRNA的表达数量性状位点。此外,他们将CNV区域中的lncRNA作为 ...
EurekAlert!
1 年
LINC00901 is an m6A-modified lncRNA and its high level is associated with poor prognosis of ...
LINC00901 is an m6A-modified lncRNA and its high level is associated with poor prognosis of PDAC patients. (A) MeRIP and lncRNA profiling identified five candidate lncRNAs in MIA PaCa-2 cells ...
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