Pancreatic cancer is a challenge due to its poor prognosis and high mortality rate, highlighting the need for new therapeutic approaches. Previous findings have shown that AUS-001 inhibits β-tubulin ...

Here, we investigate how Elongator controls microtubule dynamics. Elongator binds both to the tip of microtubules and to free GTP-tubulin heterodimers using two different subcomplexes, Elp123 and ...

You have full access to this article via your institution. There are several methods for removing MAPs from MTP to produce purified tubulin: using DEAE-Sephadex or phosphocellulose chromatography ...

SCIENCE CHINA Life Sciences近日以开放获取（OA）形式在线发表发表国家生物医学分析中心南湖实验室的满江红研究员、李爱玲研究员，与中国人民解放军总医院第一医学中心神经外科李昉晔教授题为“FSD1 inhibits glioblastoma diffuse infiltration through restriction of HDAC6-mediated microtubu ...

Ltd. (Beijing, China). Mouse IL-6 and TNF-α ELISA kits were provided by Lianke Biotechnology Co., Ltd. (Hangzhou, China). Primary antibodies against p38, p-p38, ERK, p-ERK, JNK, p-JNK, and β-Tubulin ...

目前，全世界有 6000 多万人患有阿尔茨海默病，预计到 2030 年这一数字将增至 8200 万，到 2050 年将增至 1.52 亿，目前每年的费用为 1 万亿美元。阿尔茨海默病与多种细胞变化有关，包括突触、线粒体异常、微 RNA 失调、荷尔蒙失衡和炎症反应。 在早期开发延缓衰老和预防阿尔茨海默病疾病进程的药物的努力中，美国德克萨斯理工大学P. Hemachandra Reddy等的研究团队合 ...

In a paper published in Mycology, a mycological research team described twelve new species, three new host records, and four new host and geographic records of saprobic fungi from medicinal plants in ...

The following primary antibodies were used: sheep anti-ESGP/MymX (1:1000; R&D Systems; AF4580), mouse anti-MymK (Zhang et al. 2020) (1:1000), and rabbit anti-β- Tubulin (1:1000; Cell Signaling ...

Persistent Link: https://ieeexplore.ieee.org/servlet/opac?punumber=42 ...

Several studies have demonstrated that modulating the expression of key proteins, including TGF-β, VEGF, Wnt, AQP, NF-κB, and NKCC, can significantly influence the onset and progression of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mitochondrial carrier homolog 2 (MTCH2) is a ...