Research has shown that specific genes associated with AD risk are linked to the complexity of astrocyte morphology. Alterations in these genes can lead to reduced astrocyte complexity and ...

Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...

Transplanted astrocytes displayed comparable numbers of such receptors and channels and possessed similar sizes and complexity when compared to native astrocytes. Transplanted astrocytes do appear ...

The challenge—and opportunity—lies in our ability to navigate this complexity without adding excessive layers of complicatedness. The good news is that as both external complexity and internal ...

Activated reactive astrocytes, microglia, and oligodendrocytes can undergo inflammatory reactions ... In addition, ferroptosis can further aggravate the death of DA neurons and increase inflammatory ...

Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.

“The increased complexity of our neural network probably didn’t evolve alone,” Yi said ... We relied on six well-established major cell types: excitatory and inhibitory neurons, astrocytes, microglia, ...

In this valuable manuscript, authors ablate cerebellar oligodendrocytes during postnatal development and show that synchrony of calcium transients in Purkinje neurons and behaviours are affected even ...

Glaucoma is a complex and multifactorial neurodegenerative disorder primarily characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual ...

reviewed the main functions of microglia and astrocyte cells in the developing brain and their contributions to ASD ... Moreover, this Research Topic underscores the complexity of conducting research ...

6 Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia Correspondence to Associate Professor Steve Vucic, Sydney Medical School Westmead, University of ...