Immunogenicity is critical to the success of allogeneic cell ... markers. The HepaStem cells have immunomodulatory properties, similar to other MSCs, and act on the hepatic stellate cells that ...

Histologic assessment of a liver biopsy specimen remains the gold standard for quantifying fibrosis, with increasing interest in the use of noninvasive markers to allow more frequent sampling and ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

He was actually observing two distinct cell types: Kupffer cells (liver macrophages) and hepatic stellate cells (which ... Only by integrating markers of cellular morphology and physiological ...