As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

14 Southern California Research Center for ALPD and Cirrhosis, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA The field of pancreatic stellate cell (PSC ...

The following is a summary of “Identification of a pancreatic stellate cell gene signature and lncRNA interactions associated with type 2 diabetes progression,” published in the January 2025 issue of ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

The cellular localization of AURKA was determined through double immunofluorescence staining in human fibrotic liver tissues and primary mouse hepatic stellate cells. RNA interference and AURKA ...

Expression of the receptor RAGE in biliary epithelial cells (BECs) is essential for mounting a ductular reaction (DR) in response to chronic liver injury and promoting liver fibrosis via ...

Additionally, QZRG granules suppressed the proliferation of activated hepatic stellate cells. Conclusion: Our findings suggest that QZRG granules may exert anti-fibrotic effects by downregulating ...

Background and aims: Thrombospondin 1 (TSP-1) is an important activator of latent transforming growth factor β (TGF-β) but little is known of the expression patterns and functions of TSP-1 in liver ...

Jan. 28, 2025 — The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been ... Keeping the Steps of Cell ...

Stem cells are cells that have the capacity to self-renew by dividing and to develop into more mature, specialised cells. Stem cells can be unipotent, multipotent, pluripotent or totipotent ...

Institute of Biology, University of Szczecin, Szczecin, Poland Department of Human Immunology, Institute of Medical Sciences, University of Rzeszow, Rzeszow, Poland Swiss Institute of Allergy and ...

Share on Pinterest Do all our cells have a type of memory, and if so, how might this influence health? We investigate. Design by MNT; Photography by Grant Faint/Getty Images & Ed Reschke/Getty Images.