As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

14 Southern California Research Center for ALPD and Cirrhosis, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA The field of pancreatic stellate cell (PSC ...

Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

This study aims to identify gene expression patterns specific to T2D pancreatic islet cells and to explore the potential role of pancreatic stellate cells (PSCs) in T2D progression through regulatory ...

Stellate ganglion blockade (SGB) is a practical approach to managing many clinical ... Gross macroscopic findings at the site of SGB After opening the chest, SG, a star-shaped structure, was ...

Institute of Biology, University of Szczecin, Szczecin, Poland Department of Human Immunology, Institute of Medical Sciences, University of Rzeszow, Rzeszow, Poland Swiss Institute of Allergy and ...

Jan. 28, 2025 — The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been ... Keeping the Steps of Cell ...

Background and aims: Thrombospondin 1 (TSP-1) is an important activator of latent transforming growth factor β (TGF-β) but little is known of the expression patterns and functions of TSP-1 in liver ...

The findings bolster the idea that the inflammasome has a dual role—it promotes inflammation associated with poor outcomes in late cancer stages, but early on, it can help prevent cells from ...

Dense and loose areas were observed (figure 2). In dense regions, fascicles of spindle cells were noted, along with nuclear palisading and Verocay bodies (figure 3). Nuclear atypia was occasionally ...