Many researchers working in areas outside autophagy, such as signalling, membrane trafficking, and ubiquitin-related processes, as well as researchers interested in various aspects of physiology ...

In 2000, it was suggested to me that “Autophagy will be the wave of the future; it will become the new apoptosis.” Few people would have agreed at the time, but this statement turned out to be ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end ...

Hyun remarks, "Inhibiting the activity of ubiquitin specific peptidase 14 (USP14), a component of the proteasome complex, with IU1 enhanced not only proteasome activity but also autophagy activity ...

The ubiquitin–proteasome system (UPS): both ... accelerate the deposition of both α-syn and LRRK2 protein aggregates. Autophagy: the α-syn A53T mutation seems to interfere with the chaperone ...