Cyrus Biotechnology Inc. has selected CYR-212, an engineered next-generation reduced-immunogenicity and half-life extended immunoglobulin G (IgG) protease, as a clinical development candidate for ...

This review explores the multifaceted functions of GSPT2, highlighting its involvement in cell cycle regulation and signaling pathways, as well as its potential as a tumor biomarker. By analyzing the ...

In light of these considerations, this review comprehensively synthesizes recent research findings concerning the TLR4/NF-κB signaling pathway, including the translocation of TLR4 activation to ...

This complex balances adhesion and guidance signaling to regulate neuronal migration timing and direction. This “push” signal is balanced by a “pull” signal, driven by the ubiquitin ligase ...

aDepartment of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, P.O. Box 653, Beer Sheva 84105, Israel bDepartment of Pathology and Laboratory Medicine, Rutgers-New Jersey ...

1Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan. 2Department of Pathology, University of Michigan, Ann Arbor, Michigan. Search for other works by this author ...

This cover highlights the article Deciphering the molecular logic of WOX5 function in the root stem cell organizer by Ning Zhang, Pamela Bitterli, Thomas Laux and colleagues. The image highlights the ...

is a ubiquitin- and RNA-binding protein, highly conserved in metazoans. Despite its abundance, its functions have only recently started to be characterized. Several studies have demonstrated the ...

Schematic model of the involvement of caveolin proteins, caveolae, and clathrin-coated pits in growth factor (GF) receptor binding, signaling, and subsequent internalization and degradation ... either ...