Osteoporosis is a disease in which bone resorbs faster than it is formed, gradually weakening its structure over time and ...

One major contributor to osteoporosis is estrogen deficiency, which is prevalent in postmenopausal women. Estrogen plays a vital role in maintaining bone density by inhibiting bone resorption and ...

“Our findings suggest that injectable hydrogels with localized anti-catabolic drug delivery can complement systemic ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.

Current therapies for the prevention and treatment of osteoporosis are limited by efficacy and patient compliance. RANKL/osteoprotegerin/RANK signaling regulates bone resorption and is essential ...

commonly used to treat osteoporosis. Denosumab: A monoclonal antibody that inhibits bone resorption, used in the treatment of osteoporosis. Anabolic agents: Medications that stimulate bone ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.

Researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for future fracture ...

Osteoporosis, which affects approximately ... bone begins to weaken when bone resorption exceeds bone formation. Circulating osteoclast precursor cells exacerbate bone resorption and loss by ...

Nat Clin Pract Endocrinol Metab. 2008;4(9):514-523. Whether patients with high bone-turnover rates will derive most benefit from treatments that reduce bone resorption and turnover (and vice ...