Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

When we hear the word "hepatitis," we tend to associate it with cirrhosis and other disorders affecting the liver. But it's not always ... There, they cause the swelling of brain cells called ...

One such example is the worldwide media focus on the use of sulfasalazine to treat hepatic fibrosis, with claims that half of all liver deaths could be avoided [1] even though the drug's reported ...

The rate of progression of fibrosis in an individual patient with chronic liver disease cannot be predicted with certainty. However, some general rules apply, as discussed below. 4. The precise ...

State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China ...

Additionally, QZRG granules suppressed the proliferation of activated hepatic stellate cells. Conclusion: Our findings suggest that QZRG granules may exert anti-fibrotic effects by downregulating ...

Cirrhosis is the severe scarring or fibrosis of the liver. It happens in the late stage of liver disease and other conditions that involve liver damage. The scarring that occurs with cirrhosis is ...

Aims: Aurora kinase A (AURKA) has been implicated in promoting myeloid and renal fibrosis. This study aimed to investigate the impact and underlying mechanism of AURKA on liver fibrosis and to assess ...

CLINICALLY significant liver fibrosis is a key predictor of adverse outcomes in patients with steatotic liver diseases, such as non-alcoholic fatty liver disease (NAFLD) and alcohol-related liver ...

1 Liver Research Laboratory, University of Crete School of Medicine ... The aim of this study is to investigate the role of somatostatinergic and cytokine signalling in hepatic stellate cells (HSC), ...