Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system, it's the glia that provide nutrients, clean up waste, and ...

A pathway once considered fundamental in Alzheimer’s disease is being studied intensely again, and may soon result in safer, ...

A recent study published in Cell reveals that the repeated DNA sequence that leads to Huntington’s disease (HD) expands ...

By demonstrating the role of neuronal innervations in regulating muscle metabolism and enhancing the secretion of neurotrophic factors, including myokines and exosomes, the authors have illuminated a ...

2013). The detrimental effect of GSK-3β activation on dopaminergic neuron survival was further demonstrated in transgenic mice expressing a constitutively active mutant of GSK-3β (Credle et al., 2015) ...

This scenario might lead to a pathogenic autotoxic loop promoting the spread of motor neuron pathology and disease progression. This work was supported by Institut Pasteur de Montevideo – FOCEM ...