Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness. The compounds were identified using a virtual screening approach.

Light is a powerful source of energy that is used for various biological purposes. Some organisms harness light to produce ATP, the energy currency of cells, while others use light to interpret ...

Retinal and opsin together form rhodopsin. When light energy (i.e., photons), hits a rhodopsin molecule, the shape of the molecule is altered, triggering a succession of metabolic changes leading ...

"We used a very special technique called suction-pipette recording to record the activity at such a high resolution that if one rhodopsin molecule isomerizes, or activates, we can see it ...

They further noted, “Inherited mutations in the rhodopsin gene cause retinitis pigmentosa (RP), a progressive and currently untreatable blinding disease. This study identifies small molecule ...

The authors add, "Inherited mutations in the rhodopsin gene cause retinitis pigmentosa (RP), a progressive and currently untreatable blinding disease. This study identifies small molecule ...

In addition to being the chromophore that absorbs light in the rhodopsin molecule, his research demonstrates that vitamin A controls transcription of genes relevant to vision. Zeaxanthin and lutein ...

Professor Yuki SUDO of Okayama University seeks an innovative form of treatment using rhodopsin, a protein with light-reactive qualities. By extracting it and artificially inserting it into ...

It’s actually specifically the molecule that’s in the black and white receptor cells in my eyes, the rods. It’s call Rhodopsin. And the moment I expose this to light you’ll see an ...

The authors add, "Inherited mutations in the rhodopsin gene cause retinitis pigmentosa (RP), a progressive and currently untreatable blinding disease. This study identifies small molecule ...

Treatment with bioavailable small-molecule pharmacochaperones targeting the visual receptor rhodopsin offers a promising approach to prevent retinal photoreceptor degeneration caused by inherited ...