Promoter (genetics) - Wikipedia
In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may encode a protein (mRNA), or can have a function in and of itself, such as tRNA or rRNA.
Promoter - National Human Genome Research Institute
4 天之前 · A promoter, as related to genomics, is a region of DNA upstream of a gene where relevant proteins (such as RNA polymerase and transcription factors) bind to initiate transcription of that gene. The resulting transcription produces an RNA molecule (such as mRNA).
16.6: Eukaryotic Gene Regulation - The Promoter and the ...
2024年11月23日 · The purpose of the promoter is to bind transcription factors that control the initiation of transcription. Within the promoter region, just upstream of the transcriptional start site, resides the TATA box. This box is simply a repeat of …
Promoters - Addgene
A promoter is a region of DNA where transcription of a gene is initiated. Promoters are a vital component of expression vectors because they control the binding of RNA polymerase to DNA. RNA polymerase transcribes DNA to mRNA which is ultimately translated into a functional protein.
Promoter Dynamics in Gene Regulation and Expression
2025年1月19日 · For example, mutations in the promoter region of the beta-globin gene can lead to thalassemia, a blood disorder characterized by reduced hemoglobin production. These mutations can alter the interaction between transcription factors and the promoter, leading to insufficient gene expression and subsequent disease manifestation.
Eukaryotic core promoters and the functional basis of ...
In this Review we discuss the defining properties of gene core promoters, including their sequence features, chromatin architecture, and transcription initiation patterns.
Genetic Engineering: Promoters & Marker Genes | Cambridge ...
2024年12月11日 · Genetic Engineering: Promoter. The promoter is the region of DNA that determines which gene will be expressed. This is because it is the site where RNA polymerase binds in order to begin transcription. A promoter is one example of a length of non-coding DNA that has a specific function