Adenosine kinase (AdK; EC 2.7.1.20) is an enzyme that catalyzes the transfer of gamma-phosphate from Adenosine triphosphate (ATP) to adenosine (Ado) leading to formation of Adenosine monophosphate (AMP).

Adenosine kinase (ADK) is an evolutionary ancient ribokinase derived from bacterial sugar kinases that is widely expressed in all forms of life, tissues and organ systems that tightly regulates intracellular and extracellular ADO concentrations.

This review contains the latest data on two adenosine-lowering enzymes: adenosine kinase (ADK) and adenosine deaminase (ADA). ADK deletes adenosine by its phosphorylation into 5′-adenosine monophosphate.

腺苷激酶 adenosine kinase 为核苷激酶的一种。 存在于肝脏、肾脏、酵母等。 可催化腺苷为ATP磷酸化生成5′-腺苷酸和ADP反应的酶， EC 2．7．1．20。 反应需Mg2 或Mn2 。 动物酶的最适pH=5.0，酵母酶的最适pH=6.0。 已知其它的 嘌呤碱基 、嘧啶碱基、以及黄素、烟酰胺核苷、硫胺素等也有由核苷形成核苷酸的同类酶。 腺苷激酶 adenosine kinase 为核苷激酶的一种。 存在于肝脏、肾脏、酵母等。

Adenosine kinase (ADK; EC 2.7.1.20) is an evolutionarily conserved phosphotransferase that converts the purine ribonucleoside adenosine into 5′-adenosine-monophosphate. This enzymatic reaction plays a fundamental role in determining the tone of adenosine, which fulfills essential functions as a homeostatic and metabolic regulator in all ...

Adenosine Kinase is defined as the key regulator of adenosine metabolism, catalyzing the conversion of adenosine to 5′-adenosine monophosphate. It exists in two isoforms, ADK-long localized in the nucleus and ADK-short in the cytoplasm, playing a role in epigenetic gene regulation through transmethylation reactions.

Adenosine kinase (ADK) is the key regulator of adenosine and catalyzes the metabolism of adenosine to 5'-adenosine monophosphate. The enzyme exists in two isoforms: a long isoform (ADK-long, ADK-L) and a short isoform (ADK-short, ADK-S). The two isoforms are developmentally regulated and are differe …

Adenosine kinase (AK) is a key intracellular enzyme that catalyzes the transfer of γ-phosphate from Adenosine triphosphate (ATP) to adenosine (Ado) forming Adenosine monophosphate (AMP) leading to the regulation of intra- and extracellular concentrations of adenosine.

2012年1月1日 · The enzyme adenosine kinase (AdK, ADK, or AK) plays an important role in regulating the intracellular as well as extracellular concentrations of adenosine and hence its diverse physiological actions. In view of the enormous pharmacological potential of adenosine, there has been much interest in studying adenosine kinase over the past few decades.

2017年10月16日 · The level of intracellular adenosine is regulated by the metabolism of adenosine to 5′-adenosine monophosphate (AMP) via adenosine kinase (ADK) or to inosine via adenosine deaminase (ADA).