Butenolides are a class of lactones with a four- carbon heterocyclic ring structure. [2] . They are sometimes considered oxidized derivatives of furan. The simplest butenolide is 2-furanone, which is a common component of larger natural products and …

Butenolide is a mycotoxin found in various species of fungi of the genus Fusarium. It can often be found in contaminated agricultural products. Butenolide had been implicated as the causative agent of a livestock mycotoxicosis called “fescue foot”, a peripheral vascular disorder occurring in cattle grazing on tall fescue grass.

2-Furanone is a heterocyclic organic compound. It is also known as γ-crotonolactone (GCL), as it is formally the lactone derived from γ-hydroxy isocrotonic acid. The chemical is colloquially called "butenolide", and is the parent structure for the butenolide class of …

2017年6月22日 · The transformation of syn γ-butenolide into (+)-5-hydroxy-2-piperidone 45 through a hydrogenation and subsequent deprotection sequence demonstrated the versatility of the Mannich adduct.

Butenolide is a versatile building block in chemistry that can be used for the synthesis of monocyclic and polycyclic γ-butyrolactones due to its reactive α,β-double bond, allowing for conjugate and cycloadditions.

Butenolide, like moniliformin, is a water-soluble mycotoxin produced by several Fusarium species. It co-occurs with trichothecenes and other Fusarium toxins. Since the producing fungus grows on fescue grass, butenolide was a suspected contributor to fescue toxicosis.

PD156707, a butenolide, is a selective ETA endothelin receptor antagonist Doherty et al (1995). An orally active derivative of PD012527 Doherty et al (1995), PD156707 is effective on human tissues, such as coronary artery and kidney Maguire et al (1997). It is used as a research tool to study the function of endothelin receptors.

2019年10月3日 · Butenolides | C7H8O4 | CID 139190714 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Butenolide (5-octylfuran-2(5H)-one, abbreviated as BU), structurally similar to the brominated furanones, has a core structure of 2-furanone ring, and a straight alkyl side-chain but no halogen. It was previously discovered as a non-toxic, effective antifouling compound derived from a marine Streptomyces sp. (Xu et al. 2010 ; Zhang et al. 2012 ).

2021年11月19日 · Strigolactones (SLs) and karrikins (KARs) are both butenolide molecules that play essential roles in plant growth and development. SLs are phytohormones, with SLs having known functions within the plant they are produced in, while KARs are found in ...